NIEHS has a goal to ensure job opportunities and career enhancements programs for both our work force and our community. [22] BPA-free plastics have also been introduced, which are manufactured using alternative bisphenols such as bisphenol S and bisphenol F, but there is also controversy around whether these are actually safer. 80-05-7 Bisphenol a with Wholesale Price Min. Toxicol Appl Pharmacol. Chemical name Common names and synonyms CAS number EC number Concentration; 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane: [48] BPA is a major component of several high-performance plastics, the production of these is low compared to other plastics but still equals several thousand tons a year. One reason people may be concerned about BPA is because human exposure to BPA is widespread. These studies also addressed questions about how long it takes for the body to dispose of BPA. To fix the amount of fixed bisphenol A and make excess epichlorohydrin can obtain DGEBA. The oligomers may vary in molecular weight from 340 and higher. For additional information about products that might contain bisphenol A epoxy resin, go to the Household Product Database online (http:/householdproducts.nlm.nih.gov) at the . Update on Bisphenol A (BPA) for Use in Food Contact Applications, January 2010; March 30, 2012; Updated March 2013; July 2014; November 2014. Chemical Identity. Toxicity evaluation of bisphenol a administered by gavage to sprague dawley rats from gestation day 6 through postnatal day 90. For more chemical safety facts, follow us on social media. The CLARITY Study, a 5+ year, multipronged U.S. federal government research program and the largest study ever done on BPA, confirms BPAs safety. . The site is secure. The study included an in utero phase, direct dosing to pups to mimic bottle feeding in neonates, and employed a dose range covering the low doses where effects have been previously reported in some animal studies, as well as higher doses where estrogenic effects have been measured in guideline oral studies. It is also a component in metal can coatings, which protect the food from directly contacting metal surfaces. 250/ Ton Get Latest Price. Chemical Economics Handbook. What Does U.S. Government Research Tell Us About BPA? nanocomposite based on high dielectric constant epoxy formula for embedded capacitor application. [91], BPA has been detectable in the natural environment since the 1990s and is now widely distributed. Rapid Commun Mass Spectrom. Phenol-formaldehyde resin . View our page to search various areas of interest and methodology. The results of the CLARITY Study, a 5+ year, multipronged U.S. federal government research program and the largest study ever done on BPA, confirm BPAs safety. Whether you're producing perfume or PVC plastics, the chances are intermediates will . Scientific studies show that in humans BPA is quickly metabolized and eliminated from the body. It is a thermosetting resin because of the chemical activity of the epoxy group, which can be made to open the ring by a variety of compounds containing active hydrogen and . BPA is best known for its use in the manufacture of polycarbonate plastics and epoxy resins, particularly those found in water bottles, baby bottles, and other beverage and food containers. [12] While normal exposure is below the level currently associated with risk, several jurisdictions have taken steps to reduce exposure on a precautionary basis, in particular by banning BPA from baby bottles. Health care providers depend on medical devices and equipment made with BPA for a transparent view within the human body so they can check for the presence of air bubbles or other obstructions during medical procedures. BPA is also found in epoxy resins, which act as a protective lining on the inside of some metal-based food and beverage cans. Released in 2018 by the U.S. National Toxicology Program, the data supports FDAs one word answer to the question Is BPA safe?: Yes. This process, also known as a one-step process, is commonly used for the preparation of low and medium molecular weight bisphenol A epoxy resins. It may also be used as an ingredient in some resins, which can act as a lining on the inside of some metal food and drink cans. Every day, people are exposed to a variety of activities or products that could, under certain circumstances, cause harm. On this Wikipedia the language links are at the top of the page across from the article title. Its current uses are as a primary monomer in polycarbonate plastic and epoxy resins. Industrially, a large excess of phenol is used to ensure full condensation; the product mixture of the cumene process (acetone and phenol) may also be used as starting material. #12-03 Keck Seng Tower, It can also be used in the formation of solid polymeric electrolyte for potential application in electrochemical devices. NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. [2]FDA Science Board Subcommittee on Bisphenol A. To address these questions the National Toxicology Program, partnering with FDAs National Center for Toxicological Research is carrying out in-depth studies to answer key questions and clarify uncertainties about BPA. Product. Epoxy resins produced from such epoxy monomers are called glycidyl-based epoxy resins. German Federal Institute for Risk Assessment, Japanese National Institute of Advanced Industrial Science and Technology. Alternatively, and to a much lesser extent, BPA may be ethoxylated and then converted to its diacrylate and dimethacrylate derivatives (bis-EMA, or EBPADMA). Because of these attributes, polycarbonate is used in a wide variety of common products including digital media (e.g., CDs, DVDs), electrical and electronic equipment, automobiles, sports safety equipment, reusable food and drink containers, and many other products. High-performance epoxy resins are used to make aircraft, cars, bicycles, boats, golf clubs, skis and snowboards durable, flexible and strong. Bisphenol A (BPA) is a chemical produced in large quantities for use primarily in the production of polycarbonate plastics. Epoxy resin | C21H25ClO5 | CID 169944 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Bisphenol-F can further link generating tri- and tetra-and higher phenol oligomers. Epoxy resins made with BPA are tough and readily adhere to metal surfaces, making them excellent materials for protective coatings. Since that time, the FDA has continued to review additional studies as they became available, including those addressing possible low-dose effects. These materials are much more common but their BPA content will be low. [7], BPA has been found to interact with a diverse range of hormone receptors, in both humans and animals. Farbenindustrie reported the coupling of BPA and epichlorohydrin. [2] Also in 2008, the National Toxicology Program Center for the Evaluation of Risks to Human Reproduction, part of the National Institutes of Health, released the Monograph on the Potential Human Reproductive and Developmental Effects of Bisphenol A.[3]. Toxicol Appl Pharmacol. Bisphenol A Epoxy Resin (CAS No. Toxicol Lett. Because of the way BPA is processed in the body, it is very unlikely that exposure to BPA at typical levels could cause health effects. People are generally exposed to minute levels of BPA, mostly from the ingestion of food or beverages that have been in contact with materials manufactured with BPA. Epub 2014 Feb 4. c) Doerge DR, Twaddle NC, Vanlandingham M, Fisher JW. These may be incorporated at low levels in vinyl ester resins to change their physical properties[45] and see common use in dental composites and sealants.[46][47]. Polycarbonate drinks containers are also a source of exposure, although most disposable drinks bottles are actually made of PET, which contains no BPA. Strong, shatter-resistant polycarbonate is used for helmets and protective sports visors to help protectchildren and athletes from injuries. Information about this expert consultation and the report of the meeting is available from the WHO web site. If youve ever read a news article or blog post about chemicals, you may have heard the oft-cited claim that there are 84,000 chemicals in commerce but only 200 of these have been tested for safety. FDA can make regulatory changes based on new safety or usage information. 1). Scientific studies show that in humans BPA is quickly metabolized and eliminated from the body. Pathways include photo-oxidation, or reactions with minerals such as goethite which may be present in soils and sediments. Epoxy vinyl ester resins (VER), Often shortened to vinyl esters, are an important class of high-performance thermoset molding resins. The CLARITY Study, the largest study ever done on BPA and conducted by FDA experts, confirms that BPA is safe, and supports the agencys one word answer to the question: Is BPA safe?: Yes. [33] An excess of phenol is used to ensure full condensation and to limit the formation of byproducts, such as Dianin's compound. The .gov means its official.Federal government websites often end in .gov or .mil. The next question is how do you make epoxy resin. . Studies are different, and all are not of the same quality. The site is secure. [28], The synthesis of BPA still follows Dianin's general method, with the fundamentals changing little in 130 years. It is found in various products including shatterproof windows, eyewear, water bottles, and epoxy resins that coat some metal food cans, bottle tops, and water supply pipes. Global production in 2022 is expected to reach 10 million tonnes. BPA is fairly cheap to produce, as the synthesis benefits from a high atom economy and large amounts of both starting materials are available from the cumene process. Published September 2022. In 2008 FDA released a document titled Draft Assessment of Bisphenol A for Use in Food Contact Applications. MAIN APPLICATIONS Bisphenol A Epoxy is widely used in the manufacture of: Epoxy resins; Phenolic resins . Bisphenol A is the chemical product of combining one acetone unit with two phenol groups. They are produced by the addition of - unsaturated carboxylic acids to epoxy resins. By 2009, FDA released reassessments of studies cited in the NTP Monograph in addition to other relevant studies that became available after the Monographs release. Surface chemistry the study of chemical . The reaction is catalyzed by a strong acid, such as hydrochloric acid (HCl) or a sulfonated polystyrene resin. What chemicals are in epoxy resin when you consider this? The .gov means its official. Chemical Name: Hydrogenated Bisphenol A Epoxy Resin CAS No. Health concerns have also been raised about these substitutes. Order: 18 Tons Shandong Near Chemical Co., Ltd. View larger video & image Contact Now Hot Sale Bisphenol a CAS No. Name: Bisphenol A epoxy diacrylate . [26] The utilization of BPA further expanded with discoveries at Bayer and General Electric on polycarbonate plastics. Properties of copolymer epoxy resins. [95] BPA in sediment degrades most slowly of all, particularly where this is anaerobic. Make any industrial chemical reactions run smoothly with the organic intermediate compounds available at Alibaba.com's chemical store. Scientific Peer-Review of the Draft Assessment of Bisphenol A for Use in Food Contact Applications, 31 October 2008. [66][67][68] The primary source of human exposure is via food, as epoxy and PVC are used to line the inside of food cans to prevent corrosion of the metal by acidic foodstuffs. While they have high mechanical strength values similar to epoxy resins, they are easy to apply similar to unsaturated polyester resins. [92] It is primarily a river pollutant,[93] but has also been observed in the marine environment,[94] in soils,[95] and lower levels can also be detected in air. [37] Crystals form in the monoclinic space group P 21/n (where n indicates the glide plane); within this individual molecules of BPA are arraigned with a 91.5 torsion angle between the phenol rings. Polycarbonate plastic made with BPA is shatter-resistant, lightweight, and has high optical clarity similar to glass. The chemical formula is (CH 3 ) 2 C(C 6 H 4 OH) 2. [8], Usually, the addition of acetone takes place at the para position on both phenols, however minor amounts of the ortho-para (up to 3%) and ortho-ortho isomers are also produced, along with several other minor byproducts. Compounds without a Phenanthrene Nucleus", "Bio-Based Aromatic Epoxy Monomers for Thermoset Materials", "European Union Summary Risk Assessment Report - Bis (2-ethylhexyl) Phthalate (DEHP)", "Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity of Bisphenol A Substitutes", "Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004", "The state of bisphenol research in the lesser developed countries of the EU: a mini-review", "An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment", "Bisphenol A and baby bottles: challenges and perspectives", "Consolidated federal laws of canada, Canada Consumer Product Safety Act", "MSC unanimously agrees that Bisphenol A is an endocrine disruptor - All news - ECHA", "EU court confirms BPA as substance of 'very high concern', "Estrogen biology: new insights into GPER function and clinical opportunities", "Global Assessment of Bisphenol A in the Environment: Review and Analysis of Its Occurrence and Bioaccumulation", "A critical analysis of the biological impacts of plasticizers on wildlife", Adrenosterone (11-ketoandrostenedione, 11-oxoandrostenedione), DHEA (androstenolone, prasterone; 5-DHEA), 7-Methyl-19-norandrostenedione (MENT dione, trestione), 11-Methyl-19-nortestosterone dodecylcarbonate, Normethandrone (methylestrenolone, normethisterone), Oxabolone cipionate (oxabolone cypionate), Methylclostebol (chloromethyltestosterone), Andarine (acetamidoxolutamide, androxolutamide, GTx-007, S-4), Enobosarm (ostarine, MK-2866, GTx-024, S-22), 3-Methyl-19-methyleneandrosta-3,5-dien-17-ol, 10,17-Dihydroxyestra-1,4-dien-3-one (DHED), 16,17-Epiestriol (16-hydroxy-17-estradiol), 17-Epiestriol (16-hydroxy-17-estradiol), Epiestriol (16-epiestriol, 16-hydroxy-17-estradiol), Fosfestrol (diethylstilbestrol diphosphate), Furostilbestrol (diethylstilbestrol difuroate), Triphenylmethylethylene (triphenylpropene), https://en.wikipedia.org/w/index.php?title=Bisphenol_A&oldid=1134371642, Short description is different from Wikidata, Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License 3.0, Polycyanurates can be produced from BPA by way of its di-, Bisphenol-A formaldehyde resins are a subset of, BPA is used as an antioxidant in several fields, particularly in, Several drug candidates have also been developed from bisphenol A, including, Reprinted in condensed form in: A. Dianin (1892), This page was last edited on 18 January 2023, at 10:18. [43][44] This is achieved by a reaction with epichlorohydrin under basic conditions. a) Churchwell MI, Camacho L, Vanlandingham MM, Twaddle NC, Sepehr E, Delclos KB, Fisher JW, Doerge DR. It is also known to exhibit strong endocrine-disrupting ability. Epoxy resin, on the other hand, has been of substantial significance to engineering for many decades. [90] BPA binding to ERR- preserves its basal constitutive activity. In particular, infants are considered to be at greater risk,[83] leading to bans on the use of BPA in baby bottles and related products by the US,[84] Canada,[85] and EU[86] amongst others. [11] www.who.int/foodsafety/areas_work/chemical-risks/bisphenol/en/, An official website of the United States government, : If you are giving a presentation about an environmental health topic or Products made from BPA meet high-performance demands. BPA can both mimic the action of estrogen and antagonise estrogen, indicating that it is a selective estrogen receptor modulator (SERM) or partial agonist of the ER. The reaction process is as follows: In recent years, many claims have been made about the health effects of BPA. Questions & Answers on Bisphenol A Use in Food Contact Applications, Bisphenol A Overview & Response to Petitions, European Food Safety Authority Information on Bisphenol A. [35][34], BPA has a fairly high melting point but can be easily dissolved in a broad range of organic solvents including toluene, ethanol and ethyl acetate. Some animal studies suggest that infants and children may be the most vulnerable to the effects of BPA. Toxicity evaluation of bisphenol a administered by gavage to sprague dawley rats from gestation day 6 through postnatal day 90. Bisphenol A (BPA) is a chemical building block that is used primarily to make polycarbonate plastics. Toxicol Sci. Parents and caregivers can make the personal choice to reduce exposures of their infants and children to BPA: This content is available to use on your website. Regardless, due to the scientific uncertainty, many jurisdictions have taken steps to reduce exposure on a precautionary basis. 506 epoxy resin has been used as an embedding medium for microscopy. [90] This may be the mechanism by which BPA acts as a xenoestrogen. bisphenol a epoxy resin price are designed to form other substances and play a crucial role in numerous important reactions. The synthesis of diglycidyl ether of bisphenol A (DGEBA), the most widely used epoxy resin monomer, is: Comparatively minor amounts of BPA are also used as additives or modifiers in some commodity plastics. BPA can also be found in breast milk. Reprod Toxicol. Uses of all substances that migrate from packaging into food,. Based on FDAs ongoing safety review of scientific evidence, the available information continues to support the safety of BPA for the currently approved uses in food containers and packaging. Bisphenol-A Based Epoxy Vinyl Ester Resins Home Bisphenol-A Based Epoxy Vinyl Ester Resins VE resins are a combination of both polyester resin and epoxy resins best properties. [99] Regardless, the remaining 29% of BPA will continue through to the environment, with low levels of BPA commonly observed in surface water and sediment in the U.S. and Europe. The viscosity of the PEOs obtained in present and earlier papers was compared with conventional low molecular weight bisphenol A based epoxy resin D.E.R. When government scientists review studies to make a safety conclusion, they look at the weight of the evidence, meaning the information available from all sources, and how well each study was conducted. Before sharing sensitive information, make sure you're on a federal government site. Low oral doses of bisphenol A increase volume of the sexually dimorphic nucleus of the preoptic area in male, but not female, rats at postnatal day 21. Bisphenol A (BPA) is an organic synthetic compound with the chemical formula (CH3)2C(C6H4OH)2 belonging to the group of diphenylmethane derivatives and bisphenols, with two hydroxyphenyl groups. [100], Once in the environment BPA is aerobically biodegraded by a wide a variety of organisms. A resource for kids, parents, and teachers to find fun and educational materials related to health, science, and the environment [4] The studies were evaluated for their relevance for regulatory hazard and/or risk assessment. Although many studies have been performed, these often focus on a limited range of model organisms and can use BPA concentrations well beyond environmental levels. In fact, the Federal Trade Commission has specifically cautioned that free-of claims may deceive consumers by falsely suggesting that the marketer has improved the product by removing the substance.. With more than half of the global demand, the Asian market will . As can be seen from above, the product is bisphenol A diglycidyl ether when there is sufficient epichlorohydrin and enough sodium hydroxide as the catalyst. It is alcohol, ketone and ether soluble but presents low solubility in water and carbon tetrachloride. A large number of ketones undergo analogous condensation reactions. In recent years, DGEBA has been used for the inner coating of packaging materials such as canned food. 2011 Nov;124(1):149-60. k) He Z, Paule MG, Ferguson SA. These meetings are listed in the NIEHS Events Calendar and are open to the general public. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. For example, FDA has participated with Health Canada in encouraging industry efforts to refine their manufacturing methods for the production of infant formula can linings to minimize migration of BPA into the formula. 2012 May-Jun;34(3):331-7. l) Patterson TA, Twaddle NC, Roegge CS, Callicott RJ, Fisher JW, Doerge DR. Concurrent determination of bisphenol A pharmacokinetics in maternal and fetal rhesus monkeys. . The internal rotation function of the ether bond increases the flexibility of the molecule, and the hydroxyl group enhances the chemical reactivity and the bonding ability, the epoxy group cross-links molecules into a three-dimensional network structure by reacting with a curing agent. When dropping is completed within half an hour, heat it for 12-24 hours under temperature 70-80C Stop the heating after bisphenol A is completely disappeared validated by TLC method. bisphenol A type Epoxy resin depending on the molecular weight and degree of polymerization n, the resin is yellow to amber transparent viscous liquid (or solid), the average molecular weight in the production of 300~700, n; 2, softening point below 50 is called low molecular weight epoxy resin (I. E. Soft resin); Molecular weight above 1000, n>2, those having a softening point above 60 C. The safety of a food additive is not relevant to FDAs determination regarding whether a certain use of that food additive has been abandoned. This allows exposure to be easily determined by urine testing, facilitating convenient biomonitoring of populations. Research studies pursued by FDAs National Center for Toxicological Research have [6]: Found evidence in rodent studies that the level of the active form of BPA passed from expectant mothers to their unborn offspring, following oral exposure, was so low it could not be measured. Cured epoxy resins are inert materials used as protective liners in metal cans to maintain the quality of canned foods and beverages, and have achieved wide acceptance for use as protective coatings because of their exceptional combination of toughness, adhesion, formability, and chemical resistance. The epoxide resins (also widely known as epoxy resins and, occasionally, as ethoxyline resins) are characterised by the possession of more than one 1,2-epoxy group (I) per molecule. Found that primates (including humans) of all ages effectively metabolize and excrete BPA much more rapidly and efficiently than rodents. The molecular structure of bisphenol A epoxy resin contains aromatic rings and lateral hydroxyl groups, which is beneficial to improve adhesion; in addition, the aromatic ring structure also gives the resin higher rigidity, tensile strength and thermal stability; in general, The main characteristics of bisphenol A epoxy type include: fast light curing reaction rate, high hardness and tensile strength after curing, high gloss of the film layer, and excellent chemical corrosion resistance. [27], In terms of the endocrine disruption controversy, the British biochemist Edward Charles Dodds tested BPA as an artificial estrogen in the early 1930s. While air, dust, and water are other possible sources of exposure, BPA in food and beverages accounts for the majority of daily human exposure. BPA has also been found to act as an agonist of the GPER (GPR30). Uses of all substances that migrate from packaging into food, including BPA, are subject to premarket approval by FDA as indirect food additives or food contact substances. Order: 200 kg Qingdao Cemo Technology Develop Co., Ltd. Chemical name (IUPAC): 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1 -chloro-2,3-epoxypropane, esters with acrylic acid . (2013) A new approach to synergize academic and guideline-compliant research: the CLARITY-BPA research program. After their first commercial production in the late 1940s, epoxy resins comprise a wide family of materials today. As part of its premarket review of food packaging materials, FDAs food contact regulations and food contact notification program assesses the likely migration from the packaging material to assure that any migration to food occurs at safe levels. Properties form viscous liquid Quality Level 100 composition Epoxide equivalent weight, 172-176 . Sign in to download full-size image . [9][10] The manufacturing of epoxy resins and vinyl ester resins account for 2530% of BPA use. BPA is used to make polycarbonate plastic and epoxy resins that are essential to a wide variety of consumer and industrial products, including many applications important to public health and food safety. [73] Concern is mostly related to its estrogen-like activity, although it can interact with other receptor systems as an endocrine-disrupting chemical. 2010 Oct 30;24(20):3011-20. n) Yang X, Doerge DR, Fisher JW. BPA is one of the most thoroughly tested chemicals in use today and has a safety track record of more than 50 years. It is prepared by the reaction of two equivalents of phenol with one equivalent of acetone. Toxicol Appl Pharmacol. The molecular weight and the epoxy equivalent weight are controlled by the ratio of epichlorohydrin EPC:BPA. Polymerisation is achieved by a reaction with phosgene, conducted under biphasic conditions; the hydrochloric acid is scavenged with aqueous base. . The hydroxy group may be derived from aliphatic diols, polyols (polyether polyols), phenolic compounds or dicarboxylic acids. 2011 Dec 15;207(3):298-305. f) Doerge DR, Twaddle NC, Vanlandingham M, Fisher JW. BISPHENOL A DIGLYCIDYL ETHER RESIN Chemical Properties,Uses,Production Introduction Bisphenol A diglycidyl ether (DGEBA) is a pale yellow liquid epoxy compound formed by the polycondensation of epichlorohydrin (ECH) and bisphenol A (BPA). Can obtain DGEBA under basic conditions viscosity of the same quality migrate from packaging into food, be... Coating of packaging materials such as canned food in.gov or.mil WHO web site its estrogen-like activity, it! Tested chemicals in use today and has a goal to ensure job opportunities and enhancements! 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Molecular weight from 340 and higher producing perfume or PVC plastics, the FDA has continued to review additional as! Than 50 years x27 ; s chemical store with aqueous base the niehs Events Calendar and are to... Price are designed to form other substances and play a crucial role numerous! Tough and readily adhere to metal surfaces, making them excellent materials for coatings... Career enhancements programs for both our work force and our community primary monomer bisphenol a epoxy resin chemical formula polycarbonate plastic with. Hydrochloric acid is scavenged with aqueous base follows: in recent years, many claims have been made the. And excrete BPA much more rapidly and efficiently than rodents activity, although it can interact with a diverse of! Hydroxy group may be concerned about BPA is quickly metabolized and eliminated from the article title allows to. 100 composition Epoxide equivalent weight are controlled by the reaction is catalyzed a... Humans BPA is also found in epoxy resin are tough and readily adhere to metal surfaces of epichlorohydrin EPC BPA! 506 epoxy resin, on the inside of some metal-based food and cans. Still follows Dianin 's general method, with the fundamentals changing little in years. Found to act as a primary monomer in polycarbonate plastic and epoxy resins produced from such epoxy monomers called! For 2530 % of BPA are produced by the U.S. National Toxicology Program, the FDA continued! Is aerobically biodegraded by a wide a variety of activities or products that could under... Amount of fixed bisphenol a to review additional studies as they became available, including those addressing low-dose! You consider this, they are easy to apply similar to epoxy resins and ester... [ 26 ] the manufacturing of epoxy resins precautionary basis phenol groups - unsaturated carboxylic acids to epoxy,. Substances and play a crucial role in numerous important reactions the molecular weight from 340 and higher:149-60. k He... Many claims have been made about the health effects of BPA wide family of materials today such canned... Released in 2018 by the ratio of epichlorohydrin EPC: BPA chemical product of combining one acetone with... The production of polycarbonate plastics convenient biomonitoring of populations government research Tell about...: Hydrogenated bisphenol a for use in food Contact Applications ( BPA ) is a chemical produced large... Scientific uncertainty, many claims have been made about the health effects of BPA further expanded with discoveries at and... Strong endocrine-disrupting ability block that is used primarily to make polycarbonate plastics: the CLARITY-BPA research Program into... Been found to act as a xenoestrogen, making them excellent materials for protective coatings the of! Dispose of BPA materials for protective coatings the data supports FDAs one word answer the... Body to dispose of BPA Assessment, Japanese National Institute of Advanced Science. To fix the amount of fixed bisphenol a based epoxy resin when you consider this ERR- preserves basal.: Hydrogenated bisphenol a administered by gavage to sprague dawley rats from day. Solubility in water and carbon tetrachloride, conducted under biphasic conditions ; the hydrochloric acid is scavenged with base.
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